first typical case of hla-a29 positive birdshot choroidopathy in iran

purpose: to report a typical case of hla-a29 positive birdshot choroidipathy as the first report in iran. case report: a 43-year-old male subject without any systemic disease presented complainting of decreased visual acuity in both eyes for 5 years. visual acuity was 20/30 in his right eye and cf at 2 meters in the left eye. intraocular pressure was within normal limits bilaterally. corneas and lenses were clear and no inflammation or cellular reaction was noted in the anterior chamber on slitlamp examination. the vitreous body, however showed cellular reactions. color fundus photograph, fluorescein angiography and indocyanin green were in favor of choroidopathy. in fa multiple hyperfluorescent lesions and in icg multiple hypofluorescent lesions were seen. he had been under treatment with oral prednisolone, cyclosporine and azathioprine during the past 5 years. despite initial response, the disease progressed and visual loss were progressive. regarding the course of uveitis and the fundus pattern as well as positive hla-a29, he was diagnosed with typical birdshot choroidopathy. conclusion: to our knowledge, this is the first report of a typical hla-a29 positive birdshot choroidopathy in iran. the strong association of this disease with hla-a29 confirms the diagnosis.